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Title: DETECTION OF PARTIAL DISCHARGES IN HIGH VOLTAGE POWER CAPACITOR EQUIPMENT
Author: Soumya Chouhana and Alka Thakur
Keyword: Power capacitor, insulator materials, dielectric materials.
Page No: 01-06
Abstract: Partial Discharge development of dielectric materials and their applications, including change of protecting oils, improvement of new protecting oils, and presentation of polypropylene films. This pap er presents themes in control capacitor progression and a specialized review of capacitors utilized this reproduction show MATLAB based Digital analysis of partial discharge (PDs) in control mechanical assembly is tended to. This work fills in as a reason for future examinations, to give a manual for those endeavoring to set acknowledgments levels to parameters of PD estimated utilizing advanced strategies, and to show techniques for the graphical portrayal of these parameters economically accessible partial discharge (PD) locators are depicted, alongside their essential qualities. The essential qualities that finders have in like manner and that are utilized as a reason for order are the quantity of sources of info utilized, the data transmission of the identifier, and the strategy for show handling. Subordinate test parts, which finish a coordinated test system, are examined. PD estimations for quality affirmation require a finder, as well as a whole system facilitated to augment the estimation affectability for the particular kind of mechanical assembly under test. To illustrate how an organized framework is connected, cases of a few frameworks in business utilize are release estimations on capacitor units are accounted for. The technique can be extended to the in-site diagnostic testing of power capacitors. Keywords- Power capacitor, insulator materials, dielectric materials. Download PDF


Title: VAPOUR COMPRESSION IMPROVES OF FAST COOLING AND ENERGY EFFICIENCY IN INDUSTRIAL REFRIGERATION SYSTEMS
Author: Rohit Chauhan, Prof. Sachin Baraskar, Prof. Anil Verma
Keyword: Energy efficiency, Heat transfer rate, Energy consumption and Compressors, Refrigeration system
Page No: 07-13
Abstract: Abstract: Modeling and analysis work was done on vapor compressor refrigeration system for enhance energy productivity. The system which were displayed in detail compressors have vitality use 6 to 9% lower than the units with horizontal scroll compressors and Air-cooled condensers have energy utilization 11% and auxiliary loop system have energy utilization 15%. Because of the natural concern of a global warming, endeavors have been made in supermarket [5] refrigeration industry to outline or create refrigeration system that work with less refrigerant charge and energy utilization. The "propelled" systems that have been utilized or created and have considerably less refrigerant charge than the parallel and minimal effort establishment, adaptability so as to arrange and rebuilding. Be that as it may, the independent system has some inborn weaknesses including high hardware cost and low effectiveness because of heat exchange. Keywords- Energy efficiency, Heat transfer rate, Energy consumption and Compressors, Refrigeration system Download PDF


Title: DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR THE IGURATIMOD
Author: Ravindra B. Nehete and Pushpendra Sharma
Keyword: Iguratimod, validation, development, stability indicating methodology.
Page No: 01-08
Abstract: Analytical method with accuracy, precision and stability indicting was developed for Iguratimod, achieved the required chromatographic separation by High pressure liquid chromatography (HPLC) techniqu e. HPLC method with accuracy, precision, robustness and stability indicating was developed and optimized for quantitative evaluation of Iguratimod as active pharmaceutical ingredient. Chromatographic separation for Iguratimod and its related compounds was achieved by using analytical column with stationary phase Inertsil ODS-3 (Dimension: length 150mm, internal diameter 4.6mm and particle size 5µ) and mobile phase (Buffer and acetonitrile in gradient proportion) at flow rate 1.0ml/minute with detection at 257nm. Squared correlation coefficient (r2) was observed more than 0.999 with concentration window of 12.5 to 75µg/ml. Iguratimod was retained at about 19.0±2.0 minutes. Forced degradation study for Iguratimod was carried out under the stress condition to get required degradation by using acid, base, thermal, photolytic and oxidation by hydrogen peroxide. Degradation products which are generated during stress condition did not interfere to active ingredient, Iguratimod. This analytical method optimized, validated for all the parameters specified in ICH guideline, to get results selective, accurate and precise in presence of degradation impurities. Keywords: Iguratimod, validation, development, stability indicating methodology. Download PDF


Title: A STUDY ON THE EFFECT OF EXTRACURRICULAR ACTIVITIES ON ACADEMIC ACHIEVEMENT
Author: SK Habib
Keyword: Extracurricular Activity, Academic Achievement,Senior Secondary,High Grade Point Average
Page No: 09-16
Abstract: The present study reveals the fact that involvement in the extracurricular activities produces its effect on academic performance of the students. Most of the studies have been carried out and they ha ve revealed the fact that particular extracurricular activities certainly effects on the academic achievement of the students. The purpose of this study is to establish that extra-curricular activities in which school students participate have a positive effect on their academic achievements. The study was conducted by using the questionnaire filling technique which was distributed among 171 students of the class Vlll, lX & X of Al-Ameen Mission School, Khalisani, Uluberia, Howrah, West Bengal. The study gave the fact that according to the students involved in any kind of sports, participating in dramatic and other literary activities positively affects their academic performance, while watching the television has also some positive impact on academic performance. So, it can be deduced from the study that extra-curricular activities affect academic achievements of the students and this impact also depends upon those activities in which the students are keenly involved.Download PDF


Title: STUDY THE EXTRACTION & ANTIMICROBIAL EFFICACY OF TRIPHALA
Author: Mrs. Shraddha Vikrant Gupta, Dr. Surendra Sarsaiya
Keyword: Triphala extraction, antibiotic efficacy, pharmacognostic, fruits, crude drug.
Page No: 17-19
Abstract: In the present study we have to deal with Triphala extraction and its antibiotic efficacy. Triphala is an herbal formula, contains equal proportion of the three important fruits viz. Emblica officinal is, Terminalia chebula, & Terminalia bellerica, this preparation is known to be a safe hypoglycemic agent. Its fruit is olive green in colour. From powdered crude drug using methanol as solvent, separating active material is extraction. Soxhlet assembly is used for extracting the phytochemicals. Antibiotic activity can be found by the preparation of inoculums of E.coli and S.aureus strains in NAM media. The result of present study shows that the Triphala extraction has pharmacognostic activity.Download PDF


Title: STUDY OF GROWTH, SECONDARY METABOLITIES AND GLUCOSINOLATE CONTENT IN CARDAMINE HIRSUTA V/S BRASSICA JUNCEA (INDIAN MUSTARD)
Author: Mona Kejariwal*, Dale Rodrigues and Harshada Gowda
Keyword: Cardamine hirsuta L., qualitative analysis, glucosinolates.
Page No: 20-27
Abstract: Comparative studies of secondary metabolites and glucosinolate content in Cardamine hirsuta L. v/s Brassica juncea (Indian mustard) were carried out. Comparative studies of secondary metabolites and g lucosinolate contents in Cardamine hirsuta L. v/s Brassica juncea (Indian mustard) were carried out. Physiological characteristics and analysis of secondary metabolites and glucosinolate content in Cardamine hirsuta L.and Brassica juncea was done simultaneously. Physiological characteristics of Cardamine hirsuta L. with Brassica juncea.Methods were compared with the help of U.V spectrophotometer, HPTLC and qualitative chemical analysis. Since both plants belong to Brassicaceae family, mustard plant was selected to compare physical, chemical and biological properties of Cardamine hirsuta L. Their different phytoconstituents were identified and compared qualitatively as well as quantitatively. Out of many important phytoconstituent glucosinolate was further quantified simultaneously. Secondary metabolites was identified and compared qualitatively while glucosinolate content was quantified and compared. The study revealed that raw Cardamine seeds and leaves showed maximum level of glucosinolates compared to the raw mustard seeds and leaves samples. Keywords: Cardamine hirsuta L., qualitative analysis, glucosinolates. Download PDF


Title: ANTICONVULSANT SCREENING OF HYDRO-ALCOHOLIC ROOT EXTRACT OF BERBERIS ARISTATA IN MICE
Author: Chauhan S. Suchita and Sharma K. Hemant
Keyword: Anti-convulsant, Berberis aristata, MES, Pentylenetetrazole, Diazepam, Epilepsy.
Page No: 01-06
Abstract: Objective: To explore anti-convulsant potential of hydro-alcoholic extract of Berberis aristata (B. aristata) from pentylenetetrazole-induced and maximal electroshock (MES) seizure test. Material & Me thods: The test groups receive different doses (50, 100, 250 and 500 mg/kg) of the hydro-alcoholic extract; however positive control (standard) Phenobarbitone (20 mg/kg) using for Pentylenetetrazole-induced Seizure and Diazepam (1mg/kg) used as standard for maximal electroshock induced seizure. Swiss albino mice weigh about 20-25 g of either sex selected for the investigation. Results: Phytochemical investigation reveals that occurrence of alkaloids, flavonoids in the hydro-alcoholic root extract of Berberis aristata. Acute toxicity study shows no morality action up to 1000 mg/kg dose after 72 h observation. Hydro-alcoholic extract of B. aristata offered a concentration depending upon act of pentylenetetrazole-induced seizure (PTZ) and maximal electroshock induced seizure (MES). Conclusions: These finding suggest that hydro-alcoholic extract of B. aristata remarkable effect in the treatment in epilepsy. Key-words: Anti-convulsant, Berberis aristata, MES, Pentylenetetrazole, Diazepam, Epilepsy. Download PDF


Title: 31 QBD APPROACH IN FORMULATION AND EVALUATION OF ANTIMALERIAL AND ANTIBIOTICS AS COMBINATION THERAPIES
Author: Vilas S Jadhav *and Dr. Deenanath Jhade
Keyword: Azithromycin, Chloroquine, Quality By Design, Malaria, Fix dose combination.
Page No: 07-13
Abstract: Since malaria is an illness that may rapidly progress to severe disease and even death, early diagnosis and prompt treatment of acute malaria episodes is an important strategy to reduce morbidity and mortality. The first and most important role of diagnosis is in patient management. Currently there is several medicines are available in the market and containing individual drugs. The major challenge in the malaria to provide or prescribe required dose to cure it in due course of time. The major part covered here to develop the combination therapy required to treat malaria to avoid over or low dose during the treatment. The main drug used in the treatment is Chloroquine and Azithromycin to cure in shortest period of time. In present invention, the development of fix dose combination of Azithromycin and Chloroquine required treating malaria as most effective treatment. Based on overall literature search and studies, it was found that Azithromycin 250mg and Chloroquine 200mg are most suitable strength and combination to be used to trate the malaria. The objective of the present study was to formulate suspension of Azithromycin dihydrate (AZT) and Chloroquine (CQ) as fix dose combination useful to treat Malaria. Individually, Azithromycin and Chloroquine tablets are available in the market to treat malaria. However, there is no fix treatment dose are given during treatment. The present study is to develop safest and effective fix dose combination of Azithromycin and Chloroquine tablets. Key words: Azithromycin, Chloroquine, Quality By Design, Malaria, Fix dose combination. Download PDF


Title: A REVIEW ON PHYSICOCHEMICAL ANALYSIS OF SOLID BIOMEDICAL WASTE PRODUCT OF DIFFERENT HOSPITALS OF METRO CITIES
Author: Kothawade Harshad Sharad#, Dr. Rajendra Chouksey,
Keyword: Biomedical waste, Waste disposal, Waste management, Physicochemical
Page No: 14-18
Abstract: This work discussed about Bio-medical waste’ means any solid and/or liquid waste including its container and any intermediate product, which is generated during the diagnosis, treatment or immunizatio n of human beings or animals or in research pertaining thereto or in the production or testing thereof. The physico-chemical and biological nature of these components, their toxicity and potential hazard are different, necessitating different methods / options for their treatment / disposal. Hospital waste refers to all waste generated, discarded and not intended for further use in the hospital. Improper handling of this waste affects not only medical personnel, doctors who came in contact with medical waste, but also Nurses, Para-medical staff, Ward Boy, Workers, Waste pickers and citizens at large. Solids waste generated from medical institutions need to be handled very carefully as these wastes may contain infectious material. Keywords: Biomedical waste, Waste disposal, Waste management, Physicochemical Download PDF


Title: IMPLEMENTATION OF CLEANING VALIDATION PROGRAM IN FORMULATION MANUFACTURING PLANT
Author: Pankaj P Chandratreya and Dr. Deenanath Jhade
Keyword: Validation, Cleaning Validation, Pharmaceuticals
Page No: 19-27
Abstract: Equipment cleaning and equipment cleaning validation are two activities that play a critical role in preventing risk to patients by assuring that cross-contamination between products is curtailed to a cceptable levels. Incomplete or incorrect cleaning can lead to contaminated product, with residues from previous product batches, cleaning agent and / or other extraneous material being introduced into the product manufacturing process. Cleaning validation is important as current trends show an increase in potent and complex drug substances and biotechnology products. This article will cover all elements of cleaning validation in pharma industry. Index Terms: Validation, Cleaning Validation, Pharmaceuticals Download PDF


Title: PHYSICOCHEMICAL ANALYSIS OF SOLID BIOMEDICAL WASTE PRODUCT OF DIFFERENT HOSPITALS OF METRO CITIES
Author: Kothawade Harshad Sharad#, Dr. Rajendra Chouksey
Keyword: Biomedical waste, Waste disposal, Waste management, Physicochemical
Page No: 28-33
Abstract: Biomedical waste management is increasingly being considered due to the recent regulation of biomedical waste (Management and Handling Rules, 1998). Inadequate treatment of biomedical waste can pose r isks for Health workers, patients, communities and their environment. This study was done to physicochemical Analysis of Solid Biomedical Waste Product of Different Hospital of Metro cities. Several healthcare facilities were identified using a modified questionnaire for biomedical waste management. This questionnaire was prepared by the World Health Organization (WHO) for the purpose of evaluation Treatment systems for the disposal of biomedical waste. The risks associated with the mismanagement of biomedical waste were identified in the existing system. Development of policies, plans, and waste management Protocols are recommended, in addition to the proper waste management training programs for all Health workers. Keywords: Biomedical waste, Waste disposal, Waste management, Physicochemical Download PDF


Title: OVERVIEW OF CLEANING VALIDATION IN PHARMACEUTICAL INDUSTRY
Author: Pankaj P Chandratreya and Dr. Deenanath Jhade
Keyword: Cleaning, Chemical, Decomposition Residues
Page No: 34-42
Abstract: An essential part of any pharmaceutical manufacturing facility which operates under cGMP Guidelines and adheres to Quality Systems Regulations (QSR), is the availability of well-developed and validate d cleaning procedures for all installed equipment. This will ensure that the cleaned equipment is free from residues of active ingredient from the previous product manufactured on that equipment and also from traces of detergent, if used in cleaning process. Additionally, the equipment will also be free from microbial contamination which can be carried forward into the next batch.Documented evidence that demonstrates effectiveness of the cleaning methods employed within the facility to consistently reduce potential carryover of product (including intermediates and impurities), cleaning agents and extraneous material into subsequent product to levels which are below predetermined limits is the key to produce quality products. Keywords: Cleaning, Chemical, Decomposition Residues Download PDF


Title: FORMULATION AND EVALUATION OF ANTIMALERIAL AND ANTIBIOTICS AS COMBINATION THERAPIES
Author: Vilas S Jadhav *, Dr. Deenanath Jhade
Keyword: Azithromycin, Chloroquine, Fix dose combination, Malaria, Disintegration time;
Page No: 43-48
Abstract: Since malaria is an illness that may rapidly progress to severe disease and even death, early diagnosis and prompt treatment of acute malaria episodes is an important strategy to reduce morbidity and mortality. The first and most important role of diagnosis is in patient management. Currently there is several medicines are available in the market and containing individual drugs. The major challenge in the malaria to provide or prescribe required dose to cure it in due course of time. The major part covered here to develop the combination therapy required to treat malaria to avoid over or low dose during the treatment. The main drug used in the treatment is Chloroquine and Azithromycin to cure in shortest period of time. In present invention, the development of fix dose combination of Azithromycin and Chloroquine required treating malaria as most effective treatment. Based on overall literature search and studies, it was found that Azithromycin 250mg and Chloroquine 200mg are most suitable strength and combination to be used to trite the malaria. The objective of the present study was to formulate suspension of Azithromycin dihydrate (AZT) and Chloroquine (CQ)as fix dose combination useful to treat Malaria. Individually, Azithromycin and Chloroquine tablets are available in the market to treat malaria. However, there is no fix treatment dose are given during treatment. The present study is to develop safest and effective fix dose combination of Azithromycin and Chloroquine tablets. Key words: Azithromycin, Chloroquine, Fix dose combination, Malaria, Disintegration time; Download PDF


Title: ASSOCIATION OF INDOOR AIR POLLUTION AND OTHER RISK FACTORS WITH ACUTE RESPIRATORY INFECTIONS AMONG CHILDREN IN SHEKA ZONE, SOUTH WEST ETHIOPIA
Author: Tesfaledet Tsegay,*,Worku Biyadgie
Keyword: Acute respiratory infection, Cross-Sectional survey, Logistic regression
Page No: 01-09
Abstract: Acute respiratory infections are one of the major problems of childhood in developing countries. The objective of the study was to obtain the prevalence of ARI and its risk factors among under-five ch ildren in Sheka Zone. A community based cross sectional study was conducted from October 15-26, 2016. A child is consider as having experience of ARI if the mother reported that the child had a cough in the last two weeks preceding the survey date along with short and rapid breathing. The weight and length of children were measured in every sampled home visit. Additional questions about socio-demographic status, environmental characteristics, and nutrition practice were asked. Data were entered into the computer and the Z-score nutritional variables were calculated by the Epi Info 3.5.4 package program. Further descriptive and inferential analysis carried out using IBM SPSS statistics 20. Binary logistic regression analysis has been used to show the effect of predictor variables on the incidence of acute respiratory infection. From the sampled children, the two weeks prevalence of ARI among under-five children was about 23.8% in Sheka Zone. The factors that influenced the incidence of ARI were lack of mother education, low duration of breast feeding, using unsafe fuel for cooking, absence of enough ventilation, child with mother in cooking, being malnutrition and Had Diarrhea recently. There were no associations between the stove type for cooking and kitchen place with ARI incidence. Our study revealed that Socio-demographic, indoor air pollution, health and nutritional related variables have important effect on incidence of ARI among under-five children in Sheka Zone south west Ethiopia. Key words: Acute respiratory infection, Cross-Sectional survey, Logistic regressionDownload PDF


Title: EFFECT OF DEBT FINANCING ON BUSINESS PERFORMANCE: A COMPARATIVE STUDY BETWEEN I&M BANK AND BANK OF KIGALI, RWANDA
Author: Jean Bosco Harelimana
Keyword: I&M Bank, Bank of Kigali, Business Performance.
Page No: 01-12
Abstract: The effect of debt financing on firm performance is of considerable importance to all bank business. The study is focussed on establishing the effect of debt financing on firm performance, a comparati ve study between I&M Bank and Bank of Kigali within a period of six years from 2010. The study was descriptive and correlative in nature. The study found a strong positive relationship between debt level and profitability for both I&M bank and Bank of Kigali. This tends to be less expensive and increasing it with a relatively low interest rate which leads to the increase in profit levels and hence performance. The sustainability indicators shows that, Bank of Kigali was very stable in internal financial health with average SGR of 21% and IGR of 1.7% than its competitor I&M Bank with average SGR of 10% and IGR of 0.6%. However, the debt levels are not influenced by the variation on both SGR and IGR. The study concludes that Bank of Kigali was the best financial performer than its competitor I&M Bank. These were shown by the fact that during the period of last six years, the average ROE is 21% for BK against 26% for I&M Bank , average ROA is 4% for BK against 3% for I&M Bank, average LA is 51% for BK against 47% for I&M Bank, average LD is 74% for BK against 60% for I&M Bank, average SGR is 21% for BK against 10% for I&M Bank and finally average IGR is 3% for BK against 2% for I&M Bank. Keywords: I&M Bank, Bank of Kigali, Business Performance. Download PDF


Title: TEAM WORK AND THE ACHIEVEMENT OF ORGANISATIONAL GOALS IN SELECTED COMPANIES IN LAGOS NIGERIA.
Author: Dr Jones Osasuyi Orumwense and Dr Greefield Mwakipsile
Keyword: Teamwork, organizational Goals, Lagos, Nigeria.
Page No: 13-25
Abstract: The study looked at determining the influence to teamwork towards achievement of organizational goals, a case of selected organizations in Lagos, Nigeria. The main purpose of the study was to establi sh the influence of teamwork towards achievement of organization goals in selected organization in Lagos, Nigeria. The required data was collected from various organizations in Lagos Nigeria, through questionnaire guides for primary data and secondary data being the library, internet and analyzed using SPSS. The study was conducted through descriptive survey and correlation research design, quantitative approach with a questionnaire and includes 100 respondents from selected manufacturing companies in Lagos, Nigeria. The key findings of the study reveal that; there is a strong relationship between the workers and the teamwork in their organization, the roles of team work in organization are very significant to achievement of organization goals, the level of team development in most of the organization is high, many of the respondent were not decided on this matter, most organizations do not offer rewards to its members employees who participate and promote team work for the achievement of organizational goals, team work is seen as an important tool in realization of organization’s goals and effectiveness, some organizations which do not carry out team work may not be able to attain their organizational goals to meet their minimum expectations, there is a very high relationship between teams and organizational goals, among others. The study therefore recommends that; the organizational goal by sensitizing its employee’s members to always consider it as a source of achieving set organizational goals; and also, the organizations should also consider offering rewards to those identified persons in promoting realization of organizational goals as a result of team work. Keyword: Teamwork, organizational Goals, Lagos, Nigeria. Download PDF


Title: IMPACT OF MOBILE BANKING ON FINANCIAL PERFORMANCE OF UNGUKA MICROFINANCE BANK LTD, RWANDA
Author: Jean Bosco Harelimana
Keyword: Mobile banking, financial performance, microfinance, profitability, revenue and liquidity
Page No: 26-40
Abstract: This study is for providing an analysis of the impact of mobile banking in financial performance of Unguka Bank Ltd (2012-2016). It is analyzing in depth previous studies to review the effect of mobil e banking in financial performance of Unguka Bank Ltd. Both Quantitative and Qualitative research methods such as questionnaires and interview were used towards answering the research questions in order to generate primary data. Furthermore, the study tackled on second data for attaining the objectives of the study. The questionnaires were distributed to all senior and employees who have experience with mobile banking. The interview was also administered to managers in order to fully understand the topic under research. This interview, also aimed at compensating for the eventual shortcomings of the questionnaires. On the basis of the data collected and interpreted, a number of findings and conclusions were made and presented. Findings revealed that mobile banking products offered by Unguka Bank Ltd some of which include, Fund Transfer between Accounts, Bill Payment, and order for cheque books and bank statements and mobile money. And these mobile banking products were found to have increased the revenue of Unguka ltd in the last three years. Key words: Mobile banking, financial performance, microfinance, profitability, revenue and liquidity Download PDF