JOURNALS   


Title: ECOTOURISM -ONE MEANS OF ATTEMPTING TO ACHIEVE SUSTAINABILITY
Author: Ms. Meera Ranjith, Dr. Sanjukta Sattar
Keyword: Ecotourism, Sustainable Development, Protected Areas
Page No: 01-05
Abstract: Ecotourism is a part of nature-based tourism and most of the activities of ecotourism are carried out in the natural environment. Nature is the primary element of ecotourism along with the people and culture of the place. The unique features of ecotourism include the direct interactions of the visitors with nature and culture for the purpose of enjoying, studying and admiring the natural beauty and its typical interdependences. Ecotourism activities are broadly divided into soft or hard, low-impact or high-impact, participatory or non-participatory, exploitive or active or passive, consumptive or non consumptive, and voluntary or non-voluntary. The involvement of eco-tourists in the various activities largely generate direct demand for the rooms, vehicles, guides, foods, handicrafts, etc and indirect demand for supporting services to meet the direct demand of eco-tourists. In this process, visitor expenditures induce the income of the local people and in turn, the local economy gets strengthened. Apart from the positive impacts, there are negative social, economic, cultural, environmental and ecological impacts. However, ecotourism activities create both positive and negative impacts for which maximum precautionary measures should be taken to ensure sustainable ecotourism development. Download PDF


Title: A SURVEY ON NOVEL CORONAVIRUS (nCoV) 19
Author: Bhaskar Singh and Harsh Pratap Singh
Keyword: Novel Coronavirus19, Government of India, Disease 2019, World Health Organisation.
Page No: 06-15
Abstract: Government of India is taking entirely indispensable steps to confirm that we are primed well to face the contest and hazard impersonated by the developing contagion of COVID 19 – the Corona Virus. Wi th vigorous support of the citizen of India, we have been able to comprehend the spread of the Virus in our nation. The utmost significant factor in preventing the spread of the Virus nearby is to empower the residents with the precise information and taking safeguards according to the advisories being issued by Ministry of Health and Family Welfare. In December 2019, a group of patients with pneumonia of anonymous source was linked to a seafood general market in Wuhan, China. A formerly anonymous beta coronavirus was exposed through the usage of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to segregate a novel coronavirus, named 2019-nCoV, which formed a clade inside the subgenus sarbecovirus, Orthocoronavirinae subfamily. Dissimilar from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that contaminate humans. Boosted surveillance and additional exploration are ongoing.Download PDF


Title: PREVENTION MECHANISM OF BLACK HOLE AND JAMMING ATTACK IN MOBILE AD HOC NETWORK
Author: Harsh Pratap Singh and Rashmi Singh
Keyword: Black hole attack, Jamming attack, MANET, Network Simulator
Page No: 01-07
DOI: 10.30876/JOHR.8.1.2020.01-07
Abstract: Mobile ad hoc network (MANET) is more susceptible to severe kind of security threats like denial of service attack, black hole attack, jamming attack and Sybil attack because of its dynamic behavior a nd lack of central administration. In such network any number of nodes can join or leave the network easily. In this paper, focuses on the prevention of black hole and jamming attack which is one of the serious threats. Black hole node advertises itself that it has the shortest route to destination while jamming occurs due to uninterrupted radio waves to put down the transmission between receiver and sender. We propose IDPS (Intrusion Detection and Prevention Scheme) scheme to thwart the black hole node and Distributed monitoring mechanism to choose monitor nodes responsible for identifying channel accessibility. The proposed security scheme is able to handle the jamming attack conditions and resolve the problem of link blockage from jamming. The simulation & analysis of proposed work is performed on NS-2.34 network simulator and it is found that our proposed scheme outperforms in prevention for black hole and identifying the jamming nodes.Download PDF


Title: FORMULATION DEVELOPMENT AND EVALUATION OF LOZENGES CONTAINING POLYHERBAL EXTRACT OF CINNAMOMUM TAMALA AND SPILANTHES ACMELLA
Author: Pooja C. Deshpande, Dinesh M. Biyani, Avinash O, Maske, Dr.Milind Umekar and Bhushan Hatwar
Keyword: Cinnamomum Tamala and Spilanthes Acmella extract, antimicrobial evaluation, Phytochemical screening, lozenges, evaluation parameter.
Page No: 01-10
DOI: 10.30876/JOHR.9.1.2020.01-10
Abstract: In recent year, the growing demand of herbal has lead to a quantum jump in a volume of plant material traded within and across the country. Cinnamomum Tamala and Spilanthes Acmella is an important me dicinal plant, commonly known as Tejpatta (Cinnamomum Tamala ) and Akarkara (Spilanthes Acmella) which rich source of therapeutic constituent. The aim of this research to develop of modern dosage form such as lozenges associated with an extended period of local remedy with beneficial therapeutic effect. The combination of Cinnamomum Tamala leaves and Spilanthes Acmella flowers extract exhibit antimicrobial property against the selected microorganism (staphylococcus aureus, streptococcus mutans and Escherichia coli). The qualitative Phytochemical screening of ethanol, methanol and petroleum ether extracts of both Cinnamomum Tamala leaves and Spilanthes Acmella flowers extract was performed and confirmed the presence of many phytochemicals like alkaloids, flavonoids, glycosides and triterpenes . From the result obtained it can be concluded that the optimized formula F3 was selected for the formulation of tablet lozenges and was prepared by direct compression method which exhibit optimum friability, weight uniformity, hardness and disintegration time. Download PDF


Title: FORMULATION & EVALUATION OF BUDESONIDE CONTROLLED RELEASE CAPSULES BY SUSPENSION LAYERING METHOD
Author: Verma Mithun and Gupta Vishvnath
Keyword: Multiunit Pellet Systems, Suspension Layering Method, Budesonide, Controlled Release.
Page No: 11-16
Abstract: The study was undertaken with an aim to formulate budesonide controlled release capsules. The drug budesonide is corticosteroid and used for the treatment of Crohn’s disease. Before going to develop t he formulation, a detail product literature review was carried out to know about the innovator’s product and the patent status of the drug. Preformulation study involving drug -excipients compatibility was done initially and results indicated the compatibility with all the tested excipients. The study was carried out by solution/suspension matrix layering method. In this method first drug and polymer solutions were mixed, coating was done on the sugar spheres; further enteric coating was done on polymer matrix coated pellets. Different trials were conducted with various percentages of polymer in first stage and second stage (during enteric coating), and the formulation was finally optimized based on the drug release profile. Pellets were evaluated by in vitro dissolution. These studies revealed that the F6 pellets were found to be release the drug almost comparable to that of innovator’s product. Further, the F6 formulation was subjected to release studies at different pH conditions and found to have similar release profile as that of innovator. The in vitro dissolution tests were performed and f2 values were calculated for all trials. Dissolution profile of formulation F6 matched with that of the innovator’s product and f2 value was satisfactory. Stability studies were also performed; both accelerated and long term stability studies were conducted for two months. During this study, the formulation F6 was found to be stable and no differences in the assay and release characteristics were noticed. Download PDF


Title: DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF ALBENDAZOLE DISSOLUTION STUDY
Author: Khushboo Gupta, Sudeep Mandal, Pranjul Shrivastava, Poonam Sahu
Keyword: Albendazole, UV-Vis Spectrophotometer, Recovery, Validation
Page No: 17-19
DOI: 10.30876/JOHR.9.1.2020.17-19
Abstract: Abstract:In the biopharmaceutical classification system, albendazole is a class II drug, so its dissolution analysis is very difficult due to its low solubility and difficulty in estimating product in bulk. The present study deals with the design and validation of UV spectrophotometric methods to estimate albendazole in bulk form.Albendazole is a benzimidazole derivative that has an oral wide range of activity against parasites of human and animal helminths.The drug was obeying the law of the Beer and showing good correlation.It showed a peak absorption of sodium lauryl sulphate (SLS) at 229 nm in 0.1 N HCl.Linearity of 420µg / ml was observed.The method was used in the pure, tablet and suspension forms to analyze the drug. The regression line equation slope and intercept is 0.009 and 0.017 respectively. It was found that the coefficient of correlation was 0.9996.Restoration trials have confirmed the findings of the study. The restoration has reached 97%. The method has been found to be simple, effective, fast, precise, detailed and reproducible and can be used in different dosage type and dissolution studies for routine analysis of albendazole. Download PDF


Title: Author's Guidelines
Author: Editor
Keyword: www.johronline.com
Page No: 1-3
Abstract: Manuscript must be typed on A-4 size paper with 2.54 cm. or 1” inch margin all around, with 12 font size (times new roman), single spaced in English and should be submitted via email at [email protected] ine.com or through our submission portal following the link http://www.johronline.com/submit manuscript.html together with covering letter from corresponding author as a file saved in Ms-Word (.doc). Before submitting spelling, punctuation, sentence structure and spacing should be properly checked. Download PDF


Title: COVID-19 AN EMERGING EPIDEMIC: A REVIEW
Author: Om Prakash Agrawal, CK Tyagi, Deenanath Jhade
Keyword: Conora Virus, Chloroquine, Vaccine, Hydroxychloroquine.
Page No: 01-06
DOI: 10.30876/JOHR.7.1.2020.01-06
Abstract: A novel coronavirus disease (COVID-19), triggered by infection with SARS-CoV-2, has flounced across 31 provinces in China and over 195 countries worldwide. The transition from first symptoms to acute respiratory distress syndrome (ARDS) is extremely probable to be due to unrestrained cytokine release. There is a crucial need to classify safe and active drugs for action. Chloroquine (CQ) exhibitions an inhibitory effect. However, the clinical use of CQ can cause severe side effects. Moreover, hydroxyl-chloroquine (HCQ) also exhibits an antiviral effect highly similar to that of CQ, inhibiting the cytokine storm by suppressing T-cell activation. Coronavirus vaccine will be carry after clinical trials ahead in markets.Download PDF


Title: HR MANAGEMENT AND EMPLOYEE PERFORMANCE USING ETHICS: A CRITICAL ANALYSIS
Author: Hema Rathore
Keyword: Employee Performance, Ethics, Human Resource Management, Ethical climate, HR academics.
Page No: 1-14
Abstract: Recent corporate changing aspects have led to the developing attentiveness in business ethics, both in academia and in the professional practice. Nevertheless, ethical hiatuses endure to happen in hum an resource management activities, leading HR academics and professionals to reconsideration what to do to reinvent new strategies to successfully manage ethics in HRM functions. Performance is understood as achievement of the organization in relation with its set goals. It includes outcomes achieved, or accomplished through contribution of individuals or teams to the organization‘s strategic goals. The term performance encompasses economic as well as behavioural outcomes. The objective of this critical literature review therefore is to establish the role ethics can play in human resource management to improve organizational performance. The methodology used was critical review of relevant literature with the scope of the study encompassing qualitative research of theories and comparative nature of ethics in HRM. Download PDF