ANTIDIABETIC POTENTIAL OF ALCOHOLIC EXTRACT OF ANNONA SQUAMOSA LINN. BARK IN NORMAL AND ALLOXAN INDUCED DIABETIC RATS
Abstract
Author(s): Sandeep and Abilasha Mittal
The present investigation aims to examine the diabetic potential of the plant sareefa in normal and alloxan induces diabetic rats. The barks were successively macerated with Pet. Ether (60-80), chlor oform, ethyl acetate, ethanol and water. The ethanolic extract showing the more potent chemical screening results were selected and prepared through Maceration. Alcoholic extract of bark of Annona squamosa at dose of 300 mg/Kg was given to normal and alloxan induced diabetic rats and blood samples taken from the retero-orbital plexus vein were analyzed for blood glucose level as per standard protocol with available haemoglucostrips of TOUCH blood glucometer. The comparison of blood sugar levels as per model schedule shows that in normal group the ethanolic extract, at a dose of 300 mg/Kg intra-peritoneal, the blood glucose lowering was shown which conclude, the ethanolic extract of Annona squamosa reflected anti-diabetic potential through its glucose lowering activity in experimental animals. It supported the folklore claim of anti-dibetic activity of plant. Keywords: Annona squamosa, antidiabetic, herbal remedy, sareefa,
Google Scholar citation report
Citations : 147
Journal of Harmonized Research in Pharmacy received 147 citations as per google scholar report
