Journal of Harmonized Research in Pharmacy

BENZOTRIAZOLES: A VALUABLE INSIGHT INTO RECENT DEVELOPMENTS AND BIOLOGICAL ACTIVITIES

Abstract

Author(s): Mohammad Rizwan Khan, Love Kumar Soni

In recent years, heterocyclic compounds, analogs, and derivatives have attracted strong interest due to their useful biological and pharmacological properties. The small and simple benzotriazole nuc leus is present in compounds aimed at evaluating new entities that possess anti-microbial, anti-tumor, antitubercular, anti-convulsant, anti-depressant, antimalarial, and anti-inflammatory activities. Benzotriazoles display a broad range of biological activities and are found in many potent, biologically active compounds. So far, modifications of the benzotriazole ring have proven highly effective with improved potency and lesser toxicity. The present review highlights the recently synthesized benzotriazoles possessing important biological activities.