ESTIMATION OF TOTAL FLAVONOIDS CONTENT (TFC) AND ANTI OXIDANT ACTIVITIES
OF METHANOLIC ROOT EXTRACT OF CLERODENDRUM INFORTUNATUM LINN

Pallab Kalita; Prof. (Dr.) Tapan Kumar Barman; Prof. Tapas Kumar Pal

ESTIMATION OF TOTAL FLAVONOIDS CONTENT (TFC) AND ANTI OXIDANT ACTIVITIES OF METHANOLIC ROOT EXTRACT OF CLERODENDRUM INFORTUNATUM LINN

Abstract

Author(s): Pallab Kalita, Prof. (Dr.) Tapan Kumar Barman*, Prof. Tapas Kumar Pal

Clerodendrum infortunatum(C.I.) Linn. (Lamiaceae), commonly known as Bhant in Hindi, is a small shrub occurring throughout the plains of India. This plant has been used in Indian folk medicine in the treatment of bronchitis, asthma, fever, burning sensation, diseases of the blood, inflammation, and epilepsy. The total flavonoid content of methanolic root extract of C. infortunatum (MECI) was determined by using aluminium chloride colorimetric method. It was found that Clerodendrum infortunatum root extracts contain total flavonoids in 0.0055% gm quercetin equivalent per gram of extract. In this study phytochemical analysis of methanolic extract of C. infortunatum L. has indicated the presence flavonoid . Since these compounds are of pharmacological interest, coupled with the use of this plant in traditional medicine, prompted us to check C. infortunatum L. for possible antioxidant activity by DPPH scavenging activity and reducing power ability. The maximum percentage inhibition by DPPH method was found about 92.99 at concentration of 110.46µg/ml, when compared with Quercetin. The reducing capabilities were found to be in dose dependent manner.

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