Journal of Harmonized Research in Pharmacy

MULTIPLE RARE ADVERSE EFFECTS ASSOCIATED WITH LONG TERM USE OF CARBAMAZEPINE

Abstract

Author(s): Khurshid A. Mattoo, Neha Garg

Abstract Carbamazepine an anticonvulsant and mood stabilizer drug is used primarily in the treatment of seizures in epilepsy and bipolar disorders. Also used in conditions like trigeminal neuralgia, schizophrenia and attention deficit hyperactivity disorders, the drug belongs to one of the world health organization’s list of essential medicines in a basic health system. Its use is associated with short term and long term adverse effects which range from mild to moderate to severe to fatal. The adverse reactions are also either common or rare. This article discusses a case report of a young adult female who reported with multiple rare adverse reactions to the drug involving joint, face, feet and oral cavity. Every clinician should know the possibility of such adverse reactions to help him differentiate associated conditions or diseases. Key words: Allergy, hypersensitivity, epilepsy, tegretol