Journal of Harmonized Research in Pharmacy

PHARMACOCHEMICAL CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY ASYSTASIA GANGETICA (L.) T. AND.

Abstract

Author(s): Daffodil E.D, Packia Lincy M, Pon Esakki D, Mohan V.R

The present study has been carried out to evaluate the pharmacochemical characterization and in vitro antibacterial activity of the whole plant extracts of Asystasia gangetica. Physicochemical parameters parameters (Ash value and extractive value; fluorescence analysis) and phytochemical analysis were done by using the standard methods. The petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts were tested against Bacillus thuringiensis, Streptococcus faecalis, Staphylococcus aureus, Salmonella paratyphi, Proteus vulgaris, Serratia marcescens by the agar disc diffusion method. The total ash value of whole plant of Asystasia gangetica is 10.14%.. The extractive value of water is more than in the solvents investigated. Preliminary photochemical screening of whole plant showed the presence of alkaloids, tannins, terpenoids, xanthoprotein, and sugar in the methanol and ethanol extracts. The whole plant extracts of Asystasia gangetica showed potent antibacterial activity. The present investigation, whole plant of Asystasia gangetica revealed the high degree of antibacterial against Salmonella paratyphi. The pharmacochemical characterization will be helpful to study the active principles using modern techniques in the later part of this work.

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